The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:40-1:200
Simbolo target: RHOH
Ig target: ARHH;GTP binding protein TTF;GTP-binding protein TTF;OTTHUMP00000125213;Ras homolog gene family member H;Rho related GTP binding protein;Rho related GTP binding protein RhoH;Rho-related GTP-binding protein RhoH;RHOH;RHOH;Translocation three four protein;TTF;TTF translocation three four
Area di ricerca:Signal transduction
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