Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.

Dettagli prodotto

• Codice: E-AB-18912_200μL
• Marca: Elabscience
• Specie target: Human;Rat
• Host: Rabbit
• Concentrazione: 1.02 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:300
• Simbolo target: PPP1R1A
• Ig target: I 1;I-1;I1;Inhibitor 1;IPP 1;IPP-1;IPP1;Ppp1r1a;PPR1A;Protein phosphatase 1 regulatory (inhibitor) subunit 1A;Protein phosphatase 1 regulatory subunit 1A;Protein phosphatase inhibitor 1
• Area di ricerca: Cancer;Metabolism;Signal transduction