This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:300
Simbolo target: TXNDC12
Ig target: AG1;AGR1;anterior gradient homolog 1;endoplasmic reticulum protein ERp19;endoplasmic reticulum resident protein 18;endoplasmic reticulum resident protein 19;endoplasmic reticulum thioredoxin superfamily member; 18 kDa;ER protein 18;ER protein 19;ERP 18;ERP16;ERP19;hAG 1;hAG1;hTLP19;PDIA16;protein disulfide isomerase family A; member 16;thioredoxin domain containing 12 (endoplasmic reticulum;Thioredoxin domain-containing protein 12;thioredoxin like protein p19;TLP19;TXNDC12
Area di ricerca:Cancer;Signal transduction
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