This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators.

Dettagli prodotto

• Codice: E-AB-18979_20μL
• Marca: Elabscience
• Specie target: Human;Rat
• Host: Rabbit
• Concentrazione: 0.6 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:50-1:300
• Simbolo target: ECH1
• Ig target: 4)-dienoyl-CoA isomerase;5)-Delta(2;Delta(3 5) Delta(2 4) dienoyl CoA isomerase;Delta(3 5) Delta(2 4) dienoyl CoA isomerase mitochondrial;Delta(3;Delta3 5 delta2 4 dienoyl CoA isomerase;Dienoyl CoA isomerase;ECH 1;Ech1;ECH1;Enoyl Coenzyme A hydratase 1;Enoyl Coenzyme A hydratase 1 peroxisomal;HPXEL;mitochondrial;MS1034;Peroxisomal enoyl CoA hydratase 1;Peroxisomal enoyl coenzyme A hydratase like protein
• Area di ricerca: Cancer;Cardiovascular;Metabolism;Signal transduction;Tags and Cell markers