Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:300
Simbolo target: KCTD13
Ig target: BACD1;BACURD1;BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1;BTB/POZ domain-containing protein KCTD13;FKSG86;hBACURD1;KCTD13;PDIP1;POLDIP 1;POLDIP1;Polymerase delta-interacting protein 1;Potassium channel tetramerisation domain containing 13 ;PP6832;TNFAIP1 like polymerase delta interacting protein 1;TNFAIP1-like protein
Area di ricerca:Cancer;Epigenetics and Nuclear Signaling;Metabolism;Signal transduction
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