This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:300
Simbolo target: RBFOX2
Ig target: HRNBP2;Fox 1 homologue;Fox-1 homolog B;FOX2;FXH;Hexaribonucleotide-binding protein 2;HNRBP2;RBFOX2;Repressor of tamoxifen transcriptional activity;RFOX2;RNA binding motif protein 9;RNA binding protein 9;RNA binding protein fox-1 homolog 2;RNA-binding motif protein 9;RNA-binding protein 9;RTA
Area di ricerca:Cancer;Epigenetics and Nuclear Signaling
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