GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:300
Simbolo target: GMDS
Ig target: GDP D mannose dehydratase;GDP mannose 4 6 dehydratase;GDP-D-mannose dehydratase;GDP-mannose 4;6 dehydratase;GMD;Gmds;GMDS;OTTHUMP00000017756;OTTHUMP00000232770;SDR3E1;Short chain dehydrogenase/reductase family 3E member 1
Area di ricerca:Cancer;Metabolism;Signal transduction
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