Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
Simbolo target: L3MBTL2
Ig target: 3bt like 2 protein;3bt like protein;DKFZP761I141 ;H-l(3)mbt-like protein 2;H-l(3)mbt-like protein;Hl ;Hl(3)mbt like protein ;Hl(3)mbtl ;L;l(3)mbt like 2 (Drosophila) ;l(3)mbt like 2;L(3)mbt-like 2 protein;L(3)mbt-like protein 2;L3MBTL2;Lethal;Lethal(3)malignant brain tumor-like 2 protein;Lethal(3)malignant brain tumor-like protein 2;LMBL2
Area di ricerca:Cell Biology;Epigenetics and Nuclear Signaling
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