This gene encodes a member of the adaptor-related protein complex 1, sigma subunit genes. The encoded protein is a component of adaptor protein complex 1 (AP-1), one of the AP complexes involved in claathrin-mediated vesicular transport from the Golgi or endosomes. Disruption of the pathway for display of HIV-1 antigens, which prevents recognition of the virus by cytotoxic T cells, has been shown to involve the AP-1 complex (PMID: 15569716). Alternative splicing results in multiple transcript variants.

Dettagli prodotto

• Codice: E-AB-19098_20μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 1.26 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:100-1:300
• Simbolo target: AP1S3
• Ig target: Adapter-related protein complex 1 subunit sigma-1C;Adaptor protein complex AP 1 sigma 1C subunit;Adaptor protein complex AP-1 subunit sigma-1C;Adaptor related protein complex 1 sigma 3 subunit;AP-1 complex subunit sigma-3;Ap1s3;AP1S3;Clathrin assembly protein complex 1 sigma-1C small chain;Golgi adaptor HA1/AP1 adaptin sigma-1C subunit;Sigma 1C subunit of AP-1 clathrin;Sigma-adaptin 1C;Sigma1C-adaptin