This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: WB 1:500-1:2000;IHC 1:50-1:100
Simbolo target: RNASE1
Ig target: HP-RNase;Pancreatic ribonuclease;Rib 1;RIB-1;Rib1;Ribonuclease 1;Ribonuclease A;Ribonuclease a family 1;Ribonuclease pancreatic;Ribonuclease RNase A family 1;Ribonuclease RNase A family 1 pancreatic;RNAS1_HUMAN;RNase 1;RNase A;RNase UpI-1;Rnase1;RNAseA
Area di ricerca:Epigenetics and Nuclear Signaling
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