This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Dettagli prodotto

• Codice: E-AB-19178_120μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 1.14 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:1000-1:5000;IHC 1:50-1:200
• Simbolo target: TMED10
• Ig target: 1110014C03Rik ;21 kDa transmembrane trafficking protein;21 kDa transmembrane-trafficking protein;MGC102351;p23;p24 family protein delta 1;p24 family protein delta-1;p24(DELTA);p24delta;p24delta1;S31I125;S31III125;TMED 10;Tmed10;TMEDA;Tmp 21 I;Tmp 21;Tmp 21 I;Tmp-21-I;Transmembrane emp24 domain containing protein 10;Transmembrane emp24 domain-containing protein 10;Transmembrane emp24-like trafficking protein 10 (yeast);Transmembrane protein Tmp21;Transmembrane trafficking protein 21kD
• Area di ricerca: Cancer;Neuroscience;Signal transduction