This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).

Dettagli prodotto

• Codice: E-AB-19197_120μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1.92 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:100-1:200
• Simbolo target: FYCO1
• Ig target: CATC2;CTRCT18;DKFZp779K1152;FLJ13335;FYCO1;FYCO1;FYVE and coiled coil domain containing 1;FYVE and coiled coil domain containing protein 1;FYVE and coiled-coil domain-containing protein 1;MGC126517;MGC126519;RUFY3;RUN and FYVE domain containing 3;ZFYVE7;Zinc finger FYVE domain containing protein 7;Zinc finger FYVE domain-containing protein 7
• Area di ricerca: Epigenetics and Nuclear Signaling