The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.

Dettagli prodotto

• Codice: E-AB-19259_20μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.6 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:2000
• Simbolo target: HSD3B2
• Ig target: Hydroxy-Delta-5-Steroid Dehydrogenase; 3 Beta- And Steroid Delta-Isomerase 2;3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type II;Short Chain Dehydrogenase/Reductase Family 11E; Member 2;3-Beta-HSD Adrenal And Gonadal Type;3-Beta-HSD II;3 Beta-Hydroxysteroid Dehydrogenase Type II; Delta 5-Delta 4-Isomerase Type II; 3 Beta-HSD Type II;3 Beta-Hydroxysteroid Dehydrogenase/Delta 5-->4-Isomerase Type 2;3-Beta-Hydroxy-Delta(5)-Steroid Dehydrogenase;3-Beta-Hydroxy-5-Ene Steroid Dehydrogenase.
• Area di ricerca: Cancer;Metabolism;Signal Transduction