This gene encodes a protein that contains a coiled-coil motif and C-terminal forkhead-associated (FHA) domain. The encoded protein functions as a transcriptional coactivator that increases c-Myc activity and inhibits transforming growth factor beta (TGF-beta) and nuclear factor kappa-B (NF-kB) signaling. The encoded protein also regulates the stability of cyclin D1 mRNA, and may play a role in cell proliferation and cancer progression. Mutations in this gene are a cause of psychomotor retardation, epilepsy, and craniofacial dysmorphism (PMRED).

Dettagli prodotto

• Codice: E-AB-19270_20μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 1.14 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:1000-1:5000;IHC 1:50-1:200
• Simbolo target: SNIP1
• Ig target: FHA domain containing protein SNIP1;FHA domain-containing protein SNIP1;FLJ12553;PMRED;Smad nuclear interacting protein (Smad nuclear interacting) ;smad nuclear interacting protein 1;Smad nuclear interacting protein;Smad nuclear-interacting protein 1;SNIP1 (Smad nuclear interacting protein);SNIP1;SNIP1;Splicing factor arginine/serine rich 4 (Pre mRNA splicing factor SRP75)
• Area di ricerca: Epigenetics and Nuclear Signaling;Signal transduction