This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.

Dettagli prodotto

• Codice: E-AB-19322_20μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.6 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:30-1:150
• Simbolo target: PIAS3
• Ig target: E3 SUMO protein ligase PIAS 3;E3 SUMO protein ligase PIAS3;E3 SUMO-protein ligase PIAS3;FLJ14651;OTTHUMP00000015586;OTTHUMP00000015587;PIAS 3;Pias3;PIAS3 protein;PIAS3;Protein inhibitor of activated STAT 3;Protein inhibitor of activated STAT protein 3;Protein inhibitor of activated STAT3;Zinc finger MIZ type containing 5;ZMIZ 5;ZMIZ5
• Area di ricerca: Cancer;Cell Biology;Epigenetics and Nuclear Signaling