This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.WEE1 (WEE1 G2 Checkpoint Kinase) is a Protein Coding gene. Among its related pathways are PLK1 signaling events and Cell cycle Role of 14-3-3 proteins in cell cycle regulation. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is WEE2.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:30-1:150
Simbolo target: WEE1
Ig target: DKFZp686I18166;EC 2.7.10.2;FLJ16446;MGC105683;OTTHUMP00000231338;OTTHUMP00000231339;Wee 1;WEE 1 homolog 1 (S. pombe);WEE1;WEE1 homolog (S. pombe);Wee1 homolog;WEE1 homolog S. pombe;Wee1 like protein kinase;Wee1 tyrosine kinase;Wee1+ homolog;Wee1+ S. pombe homolog;WEE1;S. pombe;homolog of;WEE1;somatic;Wee1-like protein kinase;WEE1;WEE1A;Wee1A kinase;WEE1hu
Area di ricerca:Cancer;Cell Biology;Epigenetics and Nuclear Signaling
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