The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.

Dettagli prodotto

• Codice: E-AB-19641_20μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.9 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:30-1:150
• Simbolo target: IBA57
• Ig target: C1orf69;CAF17;Chromosome 1 open reading frame 69;FLJ12734;FLJ13849;IBA57;IBA57 homolog iron sulfur cluster assembly;IBA57 iron sulfur cluster assembly homolog ;IBA57 iron sulfur cluster assembly homolog (S. cerevisiae);IBA57; S. cerevisiae; homolog of;Iron sulfur cluster assembly factor for biotin synthase and aconitase like ;iron-sulfur cluster assembly factor for biotin synthase- and aconitase-like mitochondrial proteins; with a mass of 57kDa;Iron-sulfur cluster assembly factor homolog;Mitochondrial proteins with a mass of 57kDa;MMDS3;Putative transferase C1orf69 mitochondrial;Putative transferase CAF17; mitochondrial;SPG74