This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:30-1:150
Simbolo target: CBFA2T3
Ig target: Cbfa2t3;Ccore binding factor runt domain alpha subunit 2 translocated to 3;ETO2;hMTG16;hMTG16a;hMTG16b;MTG16;MTG16;MTG8 related gene 2;MTG8 related protein MTG16a;MTG8 related protein MTG16b;MTG8-related protein 2;MTGR2;Myeloid translocation gene 8 and 16b;Myeloid translocation gene on chromosome 16 protein;Protein CBFA2T3;Zinc finger MYND domain-containing protein 4;ZMYND4
Area di ricerca:Cancer;Epigenetics and Nuclear Signaling
Newsletter TEMA RICERCA
Ricevi aggiornamenti davvero rilevanti per il tuo ambito
Inserisci la tua e-mail e seleziona le aree di interesse per ricevere le ultime novità, approfondimenti e promozioni.