This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16;21)(q24;q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Codice: E-AB-19667_200μL | Marca: Elabscience | Confezionamento: 200μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated
Dettagli prodotto
  • Codice: E-AB-19667_200μL
  • Marca: Elabscience
  • Specie target: Human;Mouse
  • Host: Rabbit
  • Concentrazione: 1.1 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
  • Isotipo: IgG
  • Clonalità: Polyclonal
  • Coniugazione: Unconjugated
  • Applicazione: IHC
  • Diluizione: IHC 1:30-1:150
  • Simbolo target: CBFA2T3
  • Ig target: Cbfa2t3;Ccore binding factor runt domain alpha subunit 2 translocated to 3;ETO2;hMTG16;hMTG16a;hMTG16b;MTG16;MTG16;MTG8 related gene 2;MTG8 related protein MTG16a;MTG8 related protein MTG16b;MTG8-related protein 2;MTGR2;Myeloid translocation gene 8 and 16b;Myeloid translocation gene on chromosome 16 protein;Protein CBFA2T3;Zinc finger MYND domain-containing protein 4;ZMYND4
  • Area di ricerca: Cancer;Epigenetics and Nuclear Signaling