Excision Repair Cross Complementing 1 (ERCC1) is a structure-specific endonuclease that is responsible for the 5'-incision during DNA repair. It forms a complex with ERCC11,XPF and ERCC4,which are required in both recombinatorial repair and nucleotide excision repair. It has been found that ERCC1,together with RRM1,are determinants of survival after surgical treatment of early-stage,non-small-cell lung cancer. (Ref: Simon,ER. 2005)

Dettagli prodotto

• Codice: E-AB-19768_200μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 1.1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:2000
• Simbolo target: ERCC1
• Ig target: COFS 4;COFS4;DNA excision repair protein ERCC 1;DNA excision repair protein ERCC-1;DNA excision repair protein ERCC1;ERCC 1;ERCC1;ERCC1;Excision repair cross complementation group 1;Excision repair cross complementing 1;Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1;Excision repair protein;RAD 10;RAD10;UV 20;UV20
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling