This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:100-1:300
Simbolo target: PROC
Ig target: Activation peptide;Anticoagulant protein C;APC;Autoprothrombin IIA;Blood coagulation factor XIV;EC 3.4.21.69;PC;proC;PROC;PROC1;Protein C (inactivator of coagulation factors Va and VIIIa);THPH3;THPH4;Vitamin K dependent protein C
Area di ricerca:Cardiovascular
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