The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:40-1:200
Simbolo target: MECOM
Ig target: Ecotropic Virus Integration Site 1 Protein Homolog;MDS1 And EVI1 Complex Locus Protein;PR Domain 3;EVI1;MDS1;MDS1 And EVI1 Complex Locus Protein EVI1;MDS1 And EVI1 Complex Locus Protein MDS1;Ecotropic Viral Integration Site 1;Myelodysplasia Syndrome 1 Protein;Zinc Finger Protein Evi1;Oncogene EVI1;AML1-EVI-1;MDS1-EVI1;RUSAT2;KMT8E;PRDM3
Area di ricerca:Cancer;Epigenetics and Nuclear Signaling
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