Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Dettagli prodotto

• Codice: E-AB-21065_200μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC-p
• Diluizione: WB 1:500-1:2000;IHC 1:100-1:300
• Simbolo target: Tak1 (phospho Thr187)
• Ig target: M3K7;MAP3K 7;Map3k7;MEKK7;Mitogen activated protein kinase kinase kinase 7;Mitogen-activated protein kinase kinase kinase 7;TAK1;TGF beta activated kinase 1;TGF-beta-activated kinase 1;TGF1a;Transforming growth factor beta activated kinase 1;Transforming growth factor-beta-activated kinase 1
• Area di ricerca: Cancer;Cardiovascular;Immunology;Signal Transduction