Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.

Dettagli prodotto

• Codice: E-AB-22002_200μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Mouse
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: Clone:2D4
• Coniugazione: Unconjugated
• Applicazione: WB;IHC-p;IF
• Diluizione: WB 1:1000-3000;IHC 1:50-300;IF 1:100-1:300
• Simbolo target: COX IV
• Ig target: AL024441;COX 4;COX IV 1;COX IV;COX IV-1;Cox4;COX41;Cox4a;COX4B;COX4I1;COX4I2;COX4L2;COXIV;Cytochrome c oxidase polypeptide IV;Cytochrome c oxidase subunit 4 isoform 1 mitochondrial;Cytochrome c oxidase subunit 4 isoform 1;mitochondrial;Cytochrome C Oxidase subunit IV;Cytochrome c oxidase subunit IV isoform 1;Cytochrome c oxidase subunit IV isoform 2 (lung);Cytochrome c oxydase subunit 4;dJ857M17.2;MGC105470;MGC72016
• Area di ricerca: Cancer;Metabolism;Signal Transduction;Tags and Cell Markers