EIF4A1 is an ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Dettagli prodotto

• Codice: E-AB-22076_200μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Mouse
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Monoclonal
• Clone: Clone:2B6
• Coniugazione: Unconjugated
• Applicazione: WB;IHC-p;IF
• Diluizione: WB 1:500-1:3000;IHC 1:50-1:300;IF 1:100-1:200
• Simbolo target: eIF4A1
• Ig target: ATP-dependent RNA helicase eIF4A-1;DDX2;DDX2A;eIF 4A I;eIF-4A-I;EIF4A;eIF4A I;eIF4A-I;EIF4A1;Eukaryotic initiation factor 4A-I;Eukaryotic initiation factor 4AI;eukaryotic translation initiation factor 4A;isoform 1;Eukaryotic translation initiation factor 4A1;IF4A1
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling