Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Codice: E-AB-22175_200μL | Marca: Elabscience | Confezionamento: 200μL

Specie: Human;Mouse;RatIsotipo: IgGClone: 3E4Coniugazione: Unconjugated

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Codice: E-AB-22175_200μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Mouse
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Monoclonal
Clone: 3E4
Coniugazione: Unconjugated
Applicazione: IHC-p
Diluizione: IHC 1:100-200
Simbolo target: IκB β
Ig target: I kappa B beta;I-kappa-B-beta;IkappaBbeta;IKB beta;IkB-B;IkB-beta;IKBB;IKBB;IkBbeta;NF kappa BIB;NF-kappa-B inhibitor beta;NF-kappa-BIB;Nfkbib;Thyroid receptor interacting protein 9;Thyroid receptor-interacting protein 9;TR interacting protein 9;TR-interacting protein 9;TRIP-9;TRIP9
Area di ricerca: Cancer;Epigenetics and Nuclear Signaling;Immunology;Signal Transduction

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