Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

Codice: E-AB-22212_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: Human;Mouse;RatIsotipo: IgGClone: Clone:1C1Coniugazione: Unconjugated

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Codice: E-AB-22212_120μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Mouse
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Monoclonal
Clone: Clone:1C1
Coniugazione: Unconjugated
Applicazione: IHC-p
Diluizione: IHC 1:100-200
Simbolo target: BAX
Ig target: Apoptosis regulator BAX;BAX;Bax-protein;BAX;BAXA;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;Bcl-2-like protein 4;BCL2 associated X protein;BCL2 associated X protein omega;BCL2 associated X protein transcript variant delta2;Bcl2-L-4;BCL2L4;membrane isoform alpha
Area di ricerca: Cancer;Cell Biology;Metabolism

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