May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Codice: E-AB-30778_20μL | Marca: Elabscience | Confezionamento: 20μL

Specie: Human;Mouse;RatIsotipo: IgGConiugazione: Unconjugated
Dettagli prodotto
  • Codice: E-AB-30778_20μL
  • Marca: Elabscience
  • Specie target: Human;Mouse;Rat
  • Host: Rabbit
  • Concentrazione: 1 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
  • Isotipo: IgG
  • Clonalità: Polyclonal
  • Coniugazione: Unconjugated
  • Applicazione: WB;IHC-p;IF
  • Diluizione: WB 1:500-2000;IHC 1:50-300;IF 1:50-300
  • Simbolo target: Caveolin-1
  • Ig target: BSCL3;CAV;CAV1;CAV1;caveolae protein;22 kD;caveolin 1 alpha isoform;caveolin 1 beta isoform;Caveolin 1 caveolae protein 22kDa;Caveolin-1;Caveolin1;cell growth-inhibiting protein 32;CGL3;LCCNS;MSTP085;OTTHUMP00000025031;PPH3;VIP 21;VIP21
  • Area di ricerca: Cancer;Cardiovascular;Metabolism;Signal Transduction;Tags and Cell Markers