This gene encodes a major glucose transporter in the mammalian blood-brain barrier. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
Ig target: Choreoathetosis/spasticity episodic (paroxysmal choreoathetosis/spasticity);CSE;DYT17;DYT18;DYT9;EIG12;erythrocyte/brain;Erythrocyte/hepatoma glucose transporter;facilitated glucose transporter member 1;Glucose transporter 1;Glucose transporter type 1;Glucose transporter type 1;erythrocyte/brain;GLUT;GLUT-1;GLUT1;GLUT1DS;GLUTB;GT1;GTG1;Gtg3;GTR1;HepG2 glucose transporter;HTLVR;Human T cell leukemia virus (I and II) receptor;MGC141895;MGC141896;PED;RATGTG1;Receptor for HTLV 1 and HTLV 2;SLC2A1;Solute carrier family 2 (facilitated glucose transporter);member 1;Solute carrier family 2;Solute carrier family 2;facilitated glucose transporter member 1
Area di ricerca:Cancer;Cardiovascular;Metabolism;Signal Transduction
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