The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
Ig target: Bpb;NEF;Protein S100-A1;S-100 protein alpha chain;S-100 protein subunit alpha;S100 alpha;S100 beta;S100 calcium binding protein A1;S100 calcium binding protein B;S100 calcium-binding protein A1;S100 protein alpha polypeptide;S100A;s100a1;S100B;S100beta;S10A1
Area di ricerca:Cancer;Neuroscience;Signal Transduction;Tags and Cell Markers
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