This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins witHuman, Mouseono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Codice: E-AB-32901_60μL | Marca: Elabscience | Confezionamento: 60μL

Specie: Human;Mouse;RatIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-32901_60μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Rabbit
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB;IHC-p;IF
Diluizione: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:50-1:200
Simbolo target: SIRT1
Ig target: 75SirT1;hSIR2;hSIRT1;HST2;S. cerevisiae;homolog of;NAD dependent deacetylase sirtuin 1;NAD dependent protein deacetylase sirtuin 1;OTTHUMP00000198111;OTTHUMP00000198112;Regulatory protein SIR2 homolog 1;SIR1;SIR2;SIR2 like 1;SIR2 like protein 1;SIR2;S.cerevisiae;homolog-like 1;SIR2-like protein 1;SIR2ALPHA;SIR2L1;Sirt1;SirtT1 75 kDa fragment;Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae);Sirtuin 1;Sirtuin type 1
Area di ricerca: Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Metabolism;Microbiology;Tags and Cell Markers

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