Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Dettagli prodotto

• Codice: E-AB-40046_100μL
• Marca: Elabscience
• Specie target: Human;Rat
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:1000
• Simbolo target: AIMP2
• Ig target: Aimp2;AIMP2;Aminoacyl tRNA synthase complex-interacting multifunctional protein 2;Aminoacyl tRNA synthetase complex interacting multifunctional protein 2;ARS interacting multi functional protein 2;JTV 1;JTV 1 protein;JTV1;JTV1 gene;Multisynthase complex auxiliary component p38;Multisynthetase complex auxiliary component p38;P38;PRO0992;Protein JTV 1;Protein JTV-1;tRNA SYNTHETASE COFACTOR p38
• Area di ricerca: Cancer;Cell Biology;Neuroscience