RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.

Codice: E-AB-40245_25μL | Marca: Elabscience | Confezionamento: 25μL

Specie: HumanIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-40245_25μL
Marca: Elabscience
Specie target: Human
Host: Rabbit
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: RAC2
Ig target: EN 7;GX;HSPC 022;HSPC022;p21 Rac 2;RAC 2;Ras related C3 botulinum toxin substrate 2;Ras related C3 botulinum toxin substrate 3 (rho family; small GTP binding protein Rac2);Ras related C3 botulinum toxin substrate 3;Rho family small GTP binding protein Rac 2;Small G protein
Area di ricerca: Cancer;Signal Transduction

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