Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70.

Dettagli prodotto

• Codice: E-AB-40660_25μL
• Marca: Elabscience
• Specie target: Human;Rat
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:1000
• Simbolo target: BAG3
• Ig target: BAG family molecular chaperone regulator 3 ;BAG-3; Bcl-2-associated athanogene 3; Bcl-2-binding protein Bis; BIS
• Area di ricerca: Cancer;Cell Biology;Metabolism