The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.

Codice: E-AB-50004_200μL | Marca: Elabscience | Confezionamento: 200μL

Specie: Human;Mouse;RatIsotipo: IgGClone: Clone:4A1Coniugazione: Unconjugated

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Codice: E-AB-50004_200μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Mouse
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Monoclonal
Clone: Clone:4A1
Coniugazione: Unconjugated
Applicazione: IHC-p
Diluizione: IHC 1:50-1:200
Simbolo target: P53 (Mono Methyl Lys370)
Ig target: Antigen NY-CO-13;BCC7;Cellular tumor antigen p53;FLJ92943;LFS1;Mutant tumor protein 53;p53;p53 tumor suppressor;P53;Phosphoprotein p53;Tp53;Transformation related protein 53;TRP53;Tumor protein 53;Tumor protein p53;Tumor suppressor p53
Area di ricerca: Cancer;Cell Biology;Epigenetics and Nuclear Signaling

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