Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress (PubMed:21266351). Binds to double-stranded RNA or DNA without sequence specificity (PubMed:25512524). Involved in development of the eye and of primordial germ cells (By similarity).

Dettagli prodotto

• Codice: E-AB-52099_120μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1.08 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:1000-1:5000;IHC 1:50-1:200
• Simbolo target: PUM3
• Ig target: HA-8;HBV X transactivated gene 5 protein;HBV X-transactivated gene 5 protein;HBV XAg-transactivated protein 5;HLA HA8;HLA-HA8;hPUF-A;K0020;Kiaa0020;KIAA0020 protein;MGC8749;Minor histocompatibility antigen HA 8;Minor histocompatibility antigen HA-8;PEN;Penguin homolog;Protein 5 transactivated by hepatitis B virus X antigen (HBxAg);Protein 5 transactivated by hepatitis B virus X antigen;PUF 6;PUF6;Pumilio domain containing protein KIAA0020;Pumilio domain-containing protein KIAA0020;RP11 526D20.2;XTP 5;XTP5
• Area di ricerca: Cell Biology