PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.

Codice: E-AB-52100_60μL | Marca: Elabscience | Confezionamento: 60μL

Specie: Human;Mouse;RatIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-52100_60μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Rabbit
Concentrazione: 1.08 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:50-1:200
Simbolo target: PCLAF
Ig target: HCV NS5A transactivated protein 9 ;HCV NS5A-transactivated protein 9;Hepatitis C virus NS5A transactivated protein 9;Hepatitis C virus NS5A-transactivated protein 9;KIAA0101;L5;NS5 ATP9;NS5ATP9;OEATC 1;OEATC;OEATC-1;OEATC1;Overexpressed in anaplastic thyroid carcinoma 1;p15(PAF);p15PAF;PAF;PAF;PCNA associated factor;PCNA-associated factor
Area di ricerca: Cancer;Cell Biology;Metabolism

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