The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Codice: E-AB-52167_120μL | Marca: Elabscience | Confezionamento: 120μL

Specie: Human;MouseIsotipo: IgGConiugazione: Unconjugated

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Codice: E-AB-52167_120μL
Marca: Elabscience
Specie target: Human;Mouse
Host: Rabbit
Concentrazione: 0.84 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: WB;IHC
Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
Simbolo target: RCHY1
Ig target: Androgen receptor N terminal interacting protein;Androgen receptor N-terminal-interacting protein;ARNIP;CH-rich-interacting match with PLAG1;CHIMP;E3 ubiquitin-protein ligase Pirh2;hARNIP;hPirh2;p53 induced protein with a RING H2 domain;p53-induced RING-H2 protein;PIRH2E;PIRH2F;PRO1996;RCHY1;Ring finger and CHY zinc finger domain containing 1 E3 ubiquitin protein ligase;RING finger and CHY zinc finger domain-containing protein 1;RING finger protein 199;RNF199;ZCHY;ZFP 363;zinc finger CHY type;Zinc finger protein 363;ZN363;ZNF363
Area di ricerca: Cancer;Cell Biology

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