This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

Dettagli prodotto

• Codice: E-AB-52200_60μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1.1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:40-1:250
• Simbolo target: PRAME
• Ig target: 4930534P07Rik;Cancer/testis antigen 130;CT130;MAPE;Melanoma antigen preferentially expressed in tumors;OIP 4;OIP-4;OIP4 ;OPA interacting protein 4;Opa interacting protein OIP4;OPA-interacting protein 4;PRAME;PRAME;Preferentially expressed antigen in melanoma ;Preferentially expressed antigen of melanoma;RP23-250F8.3
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling;Tags and Cell markers