This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Polyclonal
Coniugazione: Unconjugated
Applicazione: IHC
Diluizione: IHC 1:40-1:250
Simbolo target: RASSF8
Ig target: C12orf2;Carcinoma associated HOJ 1;Carcinoma associated protein HOJ 1;Carcinoma-associated protein HOJ-1;HoJ 1;HoJ1;Ras association (RalGDS/AF 6) domain family (N terminal) member 8;Ras association (RalGDS/AF 6) domain family 8;Ras association domain containing protein 8;Ras association domain family 8;Ras association domain-containing protein 8;RASF8;RASSF 8;Rassf8
Area di ricerca:Cancer;Signal Transduction
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