WDR77 is a component of the 20S PRMT5 (MIM 604045)-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins (see MIM 601061). This modification targets Sm proteins to the survival of motor neurons (SMN) complex (see MIM 600354) for assembly into small nuclear ribonucleoprotein core particles (Friesen et al., 2002 [PubMed 11756452]).

Dettagli prodotto

• Codice: E-AB-52236_60μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:2000
• Simbolo target: WDR77
• Ig target: 2610312E17Rik;Androgen receptor cofactor p44;C79984;HKMT1069;MEP 50;MEP-50;MEP50;MEP50;Methylosome protein 50;MGC2722;Nbla10071;p44;p44/Mep50;RGD1310479 ;RP11 552M11.3;WD repeat containing protein 77;WD repeat domain 77 ;WD repeat-containing protein 77;WDR77
• Area di ricerca: Cancer;Epigenetics and Nuclear Signaling;Signal transduction