ATG5,also named as APG5L and ASP,belongs to the ATG5 family. It is required for autophagy. It plays an important role in the apoptotic process,possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process,occurring downstream of caspase activity. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. It mediates autophagosome-independent host protection.

Codice: E-AB-81459_50μL | Marca: Elabscience | Confezionamento: 50μL

Specie: Human;Mouse;RatIsotipo: IgGClone: R05-4F2Coniugazione: Unconjugated

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Codice: E-AB-81459_50μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Rabbit
Concentrazione: 300 μg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Isotipo: IgG
Clonalità: Rabbit Monoclonal
Clone: R05-4F2
Coniugazione: Unconjugated
Applicazione: WB;IF
Diluizione: WB 1:1000-1:2000;IF 1:20-1:100
Simbolo target: APG5L
Ig target: APG 5;APG 5L;APG5;APG5 autophagy 5 like;APG5 like;APG5-like;APG5L;Apoptosis specific protein;Apoptosis-specific protein;ASP;ATG 5;Atg5;ATG5 autophagy related 5 homolog;ATG5;Autophagy protein 5;Autophagy related 5;hAPG5;Homolog of S Cerevisiae autophagy 5;OTTHUMP00000040507
Area di ricerca: Cancer;Cell Biology;Cardiovascular;Metabolism;Signal Transduction

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