FAK (Focal adhesion kinase 1) is also named as FAK1,FADK,pp125FAK,FAK and belongs to the protein kinase superfamily. It is a critical tyrosine kinase that modulates cell adhesion,migration,proliferation and survival in response to extracellular signals . It also acts as a pivotal signal 'integrator',controlling and coordinating cellular responses that include cell migration,survival,proliferation and,epithelial tissue repair after DNA damage . This protein has 6 isoforms produced by alternative promoter usage and alternative splicing.
