This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm.
Ig target: CREB regulated transcription coactivator 2;CREB-regulated transcription coactivator 2;CRTC2;CRTC2;RP11-422P24.6;TORC-2;torc2;Transducer of CREB protein 2;Transducer of regulated cAMP response element-binding protein;Transducer of regulated cAMP response element-binding protein (CREB) 2;Transducer of regulated cAMP response element-binding protein 2;Transducer of regulated CREB protein 2
Area di ricerca:Cancer;Epigenetics and Nuclear Signaling;Metabolism;Neuroscience;Signal Transduction
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