CCL27/CTACK, also known as CTACK, is a small cytokine belonging to the CC chemokine family. Members of this family are proteins characterized by two adjacent cysteines. CCL27/CTACK is chemotactic for skin-associated memory T lymphocytes. CCL27/CTACK may also play a role in mediating homing of lymphocytes to cutaneous sites. CCL27/CTACK plays a pivotal role in establishing the inflammatory infiltrate characteristic for common inflammatory skin diseases. Throμgh binding to the chemokine receptor 1 (CCR1), CCL27/CTACK mediates inflammation by promoting lymphocyte migration into the skin.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: CCL27/CTACK
Ig target: CCL;SCYA;CCL27;ALP;CTACK;CTAK;ESKINE;ILC;PESKY;SCYA27;CC Chemokine ILC;C-C Motif Chemokine 27;Cutaneous T-Cell-Attracting Chemokine;IL-11 R-Alpha-Locus Chemokine;Skinkine;Small-Inducible Cytokine A27;Chemokine (C-C motif) ligand 27;Cutaneous T cell attracting chemokine;IL 11 R alpha locus chemokine;member 27;Small inducible cytokine A27;small inducible cytokine subfamily A (Cys-Cys)
Area di ricerca:Immunology
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