Troponin I, also known as TNI and CTF1, is a 24 kDa component of a protein complex on striated muscle thin filaments. Troponin I inhibits the calcium-dependent muscle contraction mediated by Troponins C and T. The expression of cardiac Troponin I (TNNI3) is restricted to cardiac muscle, while TNNI1 and TNNI2 (encoded by distinct genes) are expressed in skeletal muscle. Mutations of cardiac Troponin I are associated with hereditary cardiomyopathy.

Dettagli prodotto

• Codice: PDEM100261_500μg
• Marca: Elabscience
• Specie target: Mouse
• Host: E.coli
• Confezionamento: Lyophilized from sterile PBS, pH 7.4.<br/>Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: Tn-I
• Ig target: Troponin I;Tnni3TNNI3Tn-I;Tnni3k
• Area di ricerca: Cardiovascular;Metabolism