This gene encodes a protein that belongs to the adenylate kinase family of enzymes. The protein has a nuclear localization and contains Walker A (P-loop) and Walker B motifs and a metal-coordinating residue. The protein may be involved in regulation of Cajal body formation. In human, AK6 and TAF9 (GeneID: 6880) are two distinct genes that share 5' exons. Alternative splicing results in multiple transcript variants.AK6 (Adenylate Kinase 6) is a Protein Coding gene. Among its related pathways are Ribosome biogenesis in eukaryotes and Purine metabolism (REACTOME). GO annotations related to this gene include ATPase activity and adenylate kinase activity.
The protein encoded by this gene catalyzes the interconversion of nucleosides, possessing both nucleoside monophosphate and diphosphate kinase activities. The encoded protein uses these interconversions to maintain nucleoside homeostasis.
A synthesized peptide derived from human AKAP10, corresponding to a region within N-terminal amino acids.
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