A synthesized peptide derived from human ANAPC4, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human ANAPC5, corresponding to a region within the internal amino acids.
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.
A synthesized peptide derived from human ANGEL2.
A synthesized peptide derived from human Angiogenin, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human Angiopoietin 1, corresponding to a region within the internal amino acids.
A synthetic peptide from human Angiopoietin 1
A synthesized peptide derived from human Angiopoietin 2, corresponding to a region within N-terminal amino acids.
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