The protein encoded by this gene belongs to the Rab family of the small GTPase superfamily. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Two transcript variants encoding different isoforms have been found for this gene.
A synthesized peptide derived from human Rab11B, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human RAB11FIP1, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human RAB11FIP2, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human Rab11-FIP4, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human RAB11FIP5, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human RAB12, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human RAB13, corresponding to a region within the internal amino acids.
This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12.
Inserisci la tua e-mail e seleziona le aree di interesse per ricevere le ultime novità, approfondimenti e promozioni.
Seleziona uno o più ambiti di interesse per ricevere comunicazioni più utili e mirate.
2025 TEMA Ricerca - All Rights Reserved.
