Ras-related protein Rab-38is aproteinthat in humans is encoded by theRAB38gene. On the basis of human genome sequence data, the RAB38 locus on chromosome 11 is flanked proximally by tyrosinase at 11q14-q21 and distally by EED at 11q14.2-q22.3 and MYO7A at 11q13.5. In melanocytic cells RAB38 gene expression may be regulated by MITF. May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1.
A synthesized peptide derived from human RAB39A, corresponding to a region within N-terminal amino acids.
Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K (PubMed:24349490). May be involved in multiple neurite formation (By similarity).
A synthesized peptide derived from human RAB39B, corresponding to a region within the internal amino acids.
This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked mental retardation.
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