A synthesized peptide derived from human Rab5A.
A synthesized peptide derived from human Rab5A, corresponding to a region within C-terminal amino acids.
Ras-related protein Rab-5A is a protein that in humans is encoded by the RAB5A gene.It is rate-limiting for homotypic early endosome fusion. It required for the fusion of plasma membranes and early endosomes,as well as contributes to the regulation of filopodia extension.
Rab5a belongs to the Rab GTPases family proteins,which play roles in endocytosis,exocytosis,and vesicular transportation. Rab family proteins were recently reported to play important roles in human cancer progression. Rab5a was reported to be overexpressed in breast and ovarian cancers and associated with proliferation and invasion.
A synthesized peptide derived from human RAB5B, corresponding to a region within C-terminal amino acids.
RAB5B (RAB5B, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Innate Immune System. Gene Ontology (GO) annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RAB5C.
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